2019 High quality Cas 59-92-7 - Andrographolide – Chenlv

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2019 High quality Cas 59-92-7 - Andrographolide – Chenlv Detail:

CAS No.: 5508-58 -7

Latin name: Andrographis Paniculata (Burm.f) Ness

Part used: whole herb

Appearance: light yellow to white powder

Molecular Formula:  C20H30O5

Molecular Weight:350.455 

Test method: HPLC

Specification:  

Andrographolide50%

Andrographolide98%

Andrographolide99%

Andrographolide is a labdane diterpenoid that is the main bioactive component of A. paniculata, a well-recognized medicinal plant in Asia. It exerts a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, antiviral, antibacterial, antidiabetic, antioxidative stress, antipyretic, antioedematogenic, and antinociceptive activities.1Andrographolide treatment inhibits nuclear factor kappa B (NF-κB) binding to DNA promoters of target genes (IC50 = ~15 μM), by forming a covalent adduct with reduced cysteine (62) of the NF-κB p50 subunit, and can also induce expression of the CYP1A subfamily of the cytochrome P450 family of enzymes.2,3 At 5 μg/g body weight it can suppress the activation of NF-κB in stimulated endothelial cells, reducing the expression of the cell adhesion molecule E-selectin, abrogating the cytokine- and endotoxin-induced peritoneal infiltration of neutrophils, attenuating septic shock, and preventing allergic lung inflammation in a mouse model of asthma.3

Product packing:  25kg/drum

Validity period: 2 years


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Sticking to the principle of "Super Quality, Satisfactory service" ,We are striving to be a good business partner of you for 2019 High quality Cas 59-92-7 - Andrographolide – Chenlv, The product will supply to all over the world, such as: Japan , Ecuador , Las Vegas , After years' creating and developing, with the advantages of trained qualified talents and rich marketing experience, outstanding achievements were gradually made. We get good reputation from the customers due to our good solutions quality and fine after-sale service. We sincerely wish to create a more prosperous and flourishing future together with all the friends home and abroad!
  • This is the first business after our company establish, products and services are very satisfying, we have a good start, we hope to cooperate continuous in the future!
    5 Stars By Murray from Macedonia - 2018.10.31 10:02
    We have been cooperated with this company for many years, the company always ensure timely delivery ,good quality and correct number, we are good partners.
    5 Stars By Camille from Romania - 2018.05.13 17:00
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