China wholesale Pharmaceutical Ingredients - Andrographolide – Chenlv Detail:
CAS No.: 5508-58 -7
Latin name: Andrographis Paniculata (Burm.f) Ness
Part used: whole herb
Appearance: light yellow to white powder
Molecular Formula: C20H30O5
Molecular Weight:350.455
Test method: HPLC
Specification:
Andrographolide50%
Andrographolide98%
Andrographolide99%
Andrographolide is a labdane diterpenoid that is the main bioactive component of A. paniculata, a well-recognized medicinal plant in Asia. It exerts a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, antiviral, antibacterial, antidiabetic, antioxidative stress, antipyretic, antioedematogenic, and antinociceptive activities.1Andrographolide treatment inhibits nuclear factor kappa B (NF-κB) binding to DNA promoters of target genes (IC50 = ~15 μM), by forming a covalent adduct with reduced cysteine (62) of the NF-κB p50 subunit, and can also induce expression of the CYP1A subfamily of the cytochrome P450 family of enzymes.2,3 At 5 μg/g body weight it can suppress the activation of NF-κB in stimulated endothelial cells, reducing the expression of the cell adhesion molecule E-selectin, abrogating the cytokine- and endotoxin-induced peritoneal infiltration of neutrophils, attenuating septic shock, and preventing allergic lung inflammation in a mouse model of asthma.3
Product packing: 25kg/drum
Validity period: 2 years
Product detail pictures:
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All we do is always associated with our tenet " Customer first, Trust first, devoting on the food packaging and environmental protection for China wholesale Pharmaceutical Ingredients - Andrographolide – Chenlv, The product will supply to all over the world, such as: moldova , Oman , Denver , Our advanced equipment, excellent quality management, research and development ability make our price down. The price we offering may not be the lowest, but we guarantee it is absolutely competitive! Welcome to contact us immediately for future business relationship and mutual success!
By Honorio from Kenya - 2017.03.08 14:45
It can be said that this is a best producer we encountered in China in this industry, we feel lucky to work with so excellent manufacturer.
By Jeff Wolfe from Algeria - 2018.04.25 16:46