Factory directly supply Polymethoxyflavnes - Arctiin – Chenlv
Factory directly supply Polymethoxyflavnes - Arctiin – Chenlv Detail:
CAS No.: 20362-31 -6
Latin name:Arctium lappa L.
Part used: fruit
Appearance: yellow brown fine powder
Molecular Formula: C27H34O11
Molecular Weight: 534.55
Test method: HPLC
Arctigenin (AR) and its glycoside, arctiin, are two major active ingredients of Arctium lappa L (A lappa), a popular medicinal herb and health supplement frequently used in Asia. In the past several decades, bioactive components from A lappa have attracted the attention of researchers due to their promising therapeutic effects. In the current article, we aimed to provide an overview of the pharmacology of AR and arctiin, focusing on their anti-inflammatory effects, pharmacokinetics properties and clinical efficacies. Compared to acrtiin, AR was reported as the most potent bioactive component of A lappa in the majority of studies. AR exhibits potent anti-inflammatory activities by inhibiting inducible nitric oxide synthase (iNOS) via modulation of several cytokines. Due to its potent anti-inflammatory effects, AR may serve as a potential therapeutic compound against both acute inflammation and various chronic diseases. However, pharmacokinetic studies demonstrated the extensive glucuronidation and hydrolysis of AR in liver, intestine and plasma, which might hinder its in vivo and clinical efficacy after oral administration. Based on the reviewed pharmacological and pharmacokinetic characteristics of AR, further pharmacokinetic and pharmacodynamic studies of AR via alternative administration routes are suggested to promote its ability to serve as a therapeutic agent as well as an ideal bioactive marker for A lappa.
Product packing: 25kg/drum
Validity period: 2 years
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All we do is often involved with our tenet " Purchaser to start with, Rely on initially, devoting over the food stuff packaging and environmental defense for Factory directly supply Polymethoxyflavnes - Arctiin – Chenlv, The product will supply to all over the world, such as: Monaco , Tanzania , Senegal , Our company regards "reasonable prices, efficient production time and good after-sales service" as our tenet. We hope to cooperate with more customers for mutual development and benefits. We welcome potential buyers to contact us.
By Colin Hazel from Madras - 2018.11.02 11:11
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By Nick from Paraguay - 2017.03.08 14:45