Factory directly supply Polymethoxyflavnes - Arctiin – Chenlv

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Factory directly supply Polymethoxyflavnes - Arctiin – Chenlv Detail:

CAS No.: 20362-31 -6

Latin name:Arctium lappa L.

Part used: fruit

Appearance: yellow brown fine powder

Molecular Formula: C27H34O11

Molecular Weight: 534.55

Test method: HPLC

Specification:

1.Arctiin10%

2.Arctiin20%

3.Arctiin40%

Arctigenin (AR) and its glycoside, arctiin, are two major active ingredients of Arctium lappa L (A lappa), a popular medicinal herb and health supplement frequently used in Asia. In the past several decades, bioactive components from A lappa have attracted the attention of researchers due to their promising therapeutic effects. In the current article, we aimed to provide an overview of the pharmacology of AR and arctiin, focusing on their anti-inflammatory effects, pharmacokinetics properties and clinical efficacies. Compared to acrtiin, AR was reported as the most potent bioactive component of A lappa in the majority of studies. AR exhibits potent anti-inflammatory activities by inhibiting inducible nitric oxide synthase (iNOS) via modulation of several cytokines. Due to its potent anti-inflammatory effects, AR may serve as a potential therapeutic compound against both acute inflammation and various chronic diseases. However, pharmacokinetic studies demonstrated the extensive glucuronidation and hydrolysis of AR in liver, intestine and plasma, which might hinder its in vivo and clinical efficacy after oral administration. Based on the reviewed pharmacological and pharmacokinetic characteristics of AR, further pharmacokinetic and pharmacodynamic studies of AR via alternative administration routes are suggested to promote its ability to serve as a therapeutic agent as well as an ideal bioactive marker for A lappa.

Product packing:  25kg/drum

Validity period: 2 years


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Our aim would be to fulfill our shoppers by offering golden company, very good value and good quality for Factory directly supply Polymethoxyflavnes - Arctiin – Chenlv, The product will supply to all over the world, such as: Moldova , Dubai , Italy , We offer OEM services and replacement parts to meet the varying needs of our customers. We offer competitive price for quality products and we will make certain your shipment is handled quickly by our logistics department. We sincerely hope to have the opportunity to meet with you and see how we can help you further your own business.
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