Andrographolide

CAS No .: 5508-58 -7

Lakina inoa: Andrographis Paniculata (Burm.f) pono

Part hoʻohana: a pau uliuli

Helehelena: mālamalama yellow i keʻokeʻo he lepo lā

Hakakino haʻilula:  C₂₀H ₃₀O ₅

Hakakino Weight: 350,455 

Ninau hoopoipoi hana: HPLC

hoakaka:  

Andrographolide50%

Andrographolide98%

Andrographolide99%

Andrographolide mea he labdane diterpenoid ia mea i ka papa kuhikuhiE bioactive ke keʻena o ka A. paniculata, he luawai-ike lāʻau lapaʻau kanu ma Asia. Ua ka lawe i ka laulā huahelu o pākōlea hana, a me immunosuppressant, antithrombotic, Anati-hoʻoʻino, antineoplastic, antiviral, antibacterial, antidiabetic, antioxidative stress, antipyretic, antioedematogenic, a me antinociceptive activities.1Andrographolide lapaʻau inhibits nukelea ololi kappa B (NF-κB) ka paa i ka DNA promoters o ka pale umauma hoʻokahi nā'ōewe (IC50 = ~ 15 μM), ma ka ho okumu i kekahi covalent adduct me hoemi cysteine ​​(62) o ka NF-κB p50 subunit, a ua hiki no hoi induce olelo o ka CYP1A subfamily o ka cytochrome P450ʻohana o nā'ūhū. 2,3 At 5 μg / g. kino ke kaupaonaʻana ka mea, ke uhi i ka ho'ā hope o NF-κB ma hauma¯na endothelial keena, hoemi i ka hōʻike o ka halepaahao mea pīlali lātoma e-selectin, abrogating ka cytokine- a me ka endotoxin-ʻonou peritoneal infiltration o neutrophils, attenuating septic hawewe, a me ka pale allergic akemāmā li nui i loko o ka iole kumu hoʻohālike o ka asthma.3

Product hāʻawe:  25kg / pahu

Ho'ōia au: 2 makahiki