High Quality for Thyme Herbal Extract - Andrographolide – Chenlv

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High-quality comes 1st; assistance is foremost; business enterprise is cooperation" is our business enterprise philosophy which is constantly observed and pursued by our business for Green Coffee Chlorogenic Acid 45% , Theaflavins , Jiaogulan Leaves Extract , We sincerely welcome domestic and foreign merchants who calls, letters asking, or to plants to negotiate, we will offer you quality products and the most enthusiastic service,We look forward to your visit and your cooperation.

High Quality for Thyme Herbal Extract - Andrographolide – Chenlv Detail:

CAS No.: 5508-58 -7

Latin name: Andrographis Paniculata (Burm.f) Ness

Part used: whole herb

Appearance: light yellow to white powder

Molecular Formula: C₂₀H₃₀O₅

Molecular Weight:350.455

Test method: HPLC

Specification:

Andrographolide50%

Andrographolide98%

Andrographolide99%

Andrographolide is a labdane diterpenoid that is the main bioactive component of A. paniculata, a well-recognized medicinal plant in Asia. It exerts a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, antiviral, antibacterial, antidiabetic, antioxidative stress, antipyretic, antioedematogenic, and antinociceptive activities.1Andrographolide treatment inhibits nuclear factor kappa B (NF-κB) binding to DNA promoters of target genes (IC50 = ~15 μM), by forming a covalent adduct with reduced cysteine (62) of the NF-κB p50 subunit, and can also induce expression of the CYP1A subfamily of the cytochrome P450 family of enzymes.2,3 At 5 μg/g body weight it can suppress the activation of NF-κB in stimulated endothelial cells, reducing the expression of the cell adhesion molecule E-selectin, abrogating the cytokine- and endotoxin-induced peritoneal infiltration of neutrophils, attenuating septic shock, and preventing allergic lung inflammation in a mouse model of asthma.3

Product packing: 25kg/drum

Validity period: 2 years

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